The boom in the use of antipsychotic medication has been particularly dramatic among children. Antipsychotic prescriptions have increased sevenfold for kids in recent years and nearly fivefold for teens and young adults aged 14 to 20, according to a 2012 study from Columbia University.
For the current study, which was published Aug. 21 in the journal JAMA Psychiatry, the researchers reviewed the records of nearly 29,000 kids aged 6 to 24 in the Tennessee Medicaid program who had recently started Shoes Nike High Tops taking antipsychotic drugs for reasons other than schizophrenia or related psychoses.
The specific antipsychotic medication used with children didn't seem to have any effect on reducing risk of diabetes.
"There aren't many antipsychotic medications that are FDA approved for use in children," Duckworth said. "When you're using a compound that doesn't have an indication, you have to be very careful about the risk/benefit assessment of that medication. You want to make sure you've reviewed all the alternative medicines and alternative strategies."
of bipolar disorder, ADHD and mood disorders such as depression, according to prior research.
By Dennis ThompsonWEDNESDAY, Aug. 21 (HealthDay News) Antipsychotic medications such as Seroquel, Abilify and Risperdal can triple a child's risk of developing type 2 diabetes within the first year of usage, according to a new study.
"In our study, we didn't see a difference between different types of drugs," Ray said. "It may be an effect of the whole class of antipsychotics." The majority of participants were taking "atypical" antipsychotics, also called second generation antipsychotics.
Dr. Ken Duckworth, medical director of the National Alliance on Mental Illness.
Antipsychotic Drugs May Triple Kids
Another expert agreed that the study results are cause for concern.
Powerful antipsychotics traditionally were used to treat schizophrenia. Now the majority of prescriptions for antipsychotic medications are for treatment Nike Sneaker Golf Shoes
The findings should lead doctors and parents to question the "off label" use of antipsychotic drugs for conditions other than schizophrenia and psychosis, said Nike Shoes Black High Tops
Within the first year, users of antipsychotic drugs had triple the risk for type 2 diabetes compared to users of other psychiatric medications.
Antipsychotics appear to increase diabetes risk by causing dramatic weight gain in children and by promoting insulin resistance, Ray said.
"Diabetes can develop relatively soon after beginning these drugs," Ray said. "We found that the risk was increased within the first year of use, and this is consistent with case reports. The risk may need to be considered even for relatively short periods of use."
Ray agreed, arguing that doctors should consider all other alternative treatments before resorting to antipsychotics.
"We found that children who received antipsychotic medications were three times as likely to develop type 2 diabetes," Ray said. "It's well known that antipsychotics cause diabetes in adults, but until now the question hadn't been fully investigated in children."
If children must be placed on antipsychotics, then doctors and parents need to keep a close eye on them for early warning signs of diabetes. "Frequent monitoring of the factors that lead to diabetes would be important, including weight and glucose intolerance," Ray said.
They compared those kids to more than 14,000 matched control patients who had started taking other types of psychiatric medications, including mood stabilizers such as lithium; antidepressants; psychostimulants such as Adderall and Ritalin; alternative ADHD medications such as clonidine and guanfacine; and anti anxiety drugs known as benzodiazepines.
and remained high for as long as a year after kids were taken off their antipsychotics. When the researchers looked only at kids 17 and younger, the findings held.
The risk continued to rise with cumulative antipsychotic dose, Nike Shoes White And Blue
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